Is it MS or is it Statin damage?

[cjbrooksjc]

Is it MS or is it Statin damage:

********************************excerpt*****************************

The objective of the MNI study was to determine the direct impact of simvastatin, a statin in clinical trials, on the integrity of myelin in the brain and on the remyelination process. The study uses a model of myelin damage that has relatively little inflammation and mimics the demyelinating aspect of MS, allowing MNI researchers to determine the direct effect of long-term statin therapy on remyelination, independent of its indirect effects mediated via immune modulation.

“The results of our study indicate that simvastatin has in fact, a slightly deleterious effect on myelin under non-pathological conditions,” adds Dr. Miron. “During remyelination, there is a decrease not only in myelin production but also in oligodendrocyte number as a result of simvastatin treatment. The findings also suggest that simvastatin inhibits CNS remyelination by blocking oligodendrocyte progenitor cell differentiation or maturation into myelinating oligodendrocytes.”

********************************link**********************************

**http://www.muhc.ca/media/news/item/?item_id=106817

Best,

Brooks