by Ray Holder » Mon Apr 20, 2009 6:17 am
Hi Gotts
Q10 is unlikely to repair the damage caused by throttling down the mevalonate pathway, but could be necessary for a long time, or even permanently, to keep body needs of Q10 satisfied.
Similarly with carnitine, if your muscle wastage is not responding to 500mg carnitine a day, you are not taking enough to satisfy your needs, statins having damaged the natural supply.
I would suggest that you are not taking enough of each one, in my advanced age, I take 1200 mg Q10 a day, and 12 grams L carnitine, but I also need carnitine for late effects of polio, besides which, both are needed to ward off heart failure problems.
Try adding to one thing at a time, so you know which is helping, your leg muscle should respond over weeks to more carnitine, probably at least 3-4 grammes a day, but get up to that level gradually, or your bowels will object, in fact it is sometimes recommended to increase gradually to bowel intolerance, and then reduce by 250 mg a day.
I should wait a few weeks to see if extra LCarnitine is making improvement, before adding to your Q10 dose, although I suspect you need 500 or more mg daily, but if you change two things at the same time, you cannot be sure which is working on what symptom.
I fear that over here, prices are increasing fast, due to currency value variations, but US web prices seem to stay fairly static, so best of luck!!
Ray