Official Airline incident report of passenger airliner copilot who became disoriented and mentally confused in flight, had to be forcibly removed from the cockpit and restrained by the flight crew, and who subsequently recovered following an 11 day stay in a mental hospital.
*http://www.aaiu.ie/upload/general/11139-0.pdf
My first thought was that this might have been Dr. Graveline's nightmare of a pilot on Lipitor being mentally incapacitated in flight. I do not know if the copilot in question was on statins, but this does appear to fulfill the worst-case scenario.