by Ray Holder » Tue Jul 25, 2006 9:40 am
Hi Sheltie57
I think the reason for the withdrawal of carnitine in Canada must be something to do with an item I read saying that there are some supplies of faulty Chinese carnitine in circulation.
We use L carnitine, but there is also a D (dexter) version, which has the same chemical composition, but the molecules are a right hand version, while the L or levo is the left hand variety. The D version can be harmful, and is sometimes found along with L in poor quality carnitine.
I presume Canada Health has clamped down on it for that reason, but that is not very helpful for the likes of us, and the UK version of Carnitor, the licensed drug version, would cost me £700 a month, compared to the £100 which I now pay.
I have been a bit troubled about the use over there of Acyl Carnitine, which I tried in the beginning and found less than useful. I have tried to find a helpful website on this, it is difficult to find one which doesn't fly off into the realms of obscure associated actions in the mitochondria, but it appears that L carnitine is needed to carry fat into the mitochondria as fuel, and then it becomes acyl to carry the "combustion" products away.
Now I never had muscle pain, only wastage, but I started off, after polio, with a shortage of glucose fuelled muscle, and I had to rely much more on fat and Lcarnitine for energy and to keep the muscle from damage.
As a result I did not have the waste products of glucose "burning" to dispose of, only the reduced amount from fat. As you folk had a lot of muscle pain, which I believe was due to accumulated waste products needing acyl carnitine to get away, then acyl works for you, up to a point.
You probably have still a good amount of glucose burning muscle left to keep you going, but if you are not getting enough L carnitine to service the fat-needing muscles, you will not prevent slow wastage of that part of each muscle's bulk. My wasted muscle gained a considerable amount over the first few months of carnitine use.
These are only my thoughts, and someone may know more about this complex subject than I have been able to glean from the web, and it needs some careful consideration to avoid any long term problems.