by Biologist » Wed Jun 25, 2008 6:10 pm
I plan to buy it again -- a lot of it. This week. My thinking was that it was effective when I used it, but when I ran out last time, I did not get around to reordering. That was many weeks / months ago. Recently, besides your post, I have heard / read other endorsements for it.
I use to put two of the tiny pills in my mouth and crush them a bit with my teeth and then put them under my tongue to dissolve while I took a rest / nap. (I rarely need to take such naps any more unless I slept real poorly the night before.) I think that works (i.e., sublingually). Seems like you are instructed to take it / them on an empty stomach so that it can pass through your stomach undigested (like a buffered aspirin) to be better absorbed beyond the stomach (i.e., intestines) or the molecule will be denatured. Not supposed to lie back down in bed for 15 or 30 minutes if you take it on waking. That is why I started doing it sublingually later in the day as I did not want to wait around prior to breakfast (but that's silly and not really a problem waiting a while to eat). I cannot be sure that it was getting absorbed the way I was doing it. This time I will play it straight by the directions. Hard to believe that small of a pill could be so potent, but apparently it is. Thanks for mentioning it. I will post on my results in a few weeks. My left shoulder pain seems to be persistent. It's sure back recently. But it has been almost completely gone for some weeks at a time before. I think the NADH maybe a real good idea.
I may update a post I did many months ago regarding Botox before too long (but if not, this paragraph will have to suffice; please pardon the temporary tread hyjacking). In short, it again set me back a bit (temporarily hopefully, until it wears off after about three months again). It made my left arm and leg and shoulder noticeably weaker and I can feel it a bit on my right side too (which otherwise is nearly normal). My left achiles tendon started acting up and there is a new "clicking" feeling / sensation in that ankle with every step (implying a weakening of surrounding and supporting joint musculature there). Some statin-related damage immolates ALS and ALS is the only contraindication listed for Botox. (I use it to prevent tension headaches and also cosmetically as it keeps me from looking like I am squiting or looking like I am angry; and it works wonders for me.) For the next trial in six months or so (or whenever I feel brave), I will be doing my own method for administration (or I will refuse to do it ever again) which will entail many more injections but less than half the amount of Botox solution in all. The problem is that way too much is going directly into systemic circulation in the blood stream and only a small amount is remaining in the facial muscle sites where it is injected. (I get it in about four small shots between the eyes.) The doctor is making the shot depots way to large for me. For "normal people" this is not a problem (actually it probably IS a problem, it's just a bit too subtle to be noticed, but I theorize it does cause some degree of unwanted paralysis in skeletal muscles for everyone which people would like to avoid if they knew it was happening). I will also fabricate a simple cardboard face piece (from an empty toilet paper cylinder maybe) to wear with a rubber band around my head (i.e., "mask-like thing" above the eyes) for an hour or two right afterwards to restrict blood flow in and out of that area for a while. My guess is that this is likely to be very successful. (Listening BigPharma?) I will likely have to do it myself (inject myself) and figure out how to get the Botox (I have several options) since the doctor is not the type to experiment. He did not listen to my suggestion last time (about numerous smaller injections) and told me what I already knew that the drug needs to be in the "belly of the muscle." No sh*t Sherlock. In fact, it needs to be in several locations "in the belly of the muscle" and not outflowing into systemic circulation. (Also it will cost about half as much as only half as much or less will be used -- it's sold by the "unit.") BTW, he also started Lipitor a year or two ago as part of preventative medicine for himself. ("That stuff sure does work!") And he does not seem to be catching on very fast regardless of my warnings to him including a lowering of IQ. Appears to be a slow learner. (Actually he' just a typical Know-it-all In-BigPharma-we-trust-type like I use to be). He'll learn. Eventually. Well, this will be the update then as it is already so long -- I may link to this post from that thread sometime. The other thing I noticed is some slight "depression" and/or headaches in the mornings and maybe all day long (where I just get use to it). Barely noticeable, but it is there and may have happened last time a bit too as I remember. This time I happened to be taking a small dosage of Cialis at the time. A couple of days after the Botox, I read that Cialis and Viagra are being used recently to help escort drugs across the blood brain barrier. Wonderful (sarcasm there). The Botox toxin is just barely too large to cross on its own per the literature, but the Cialis would likely have done the trick (more nitric oxide relaxes the endothelium cells to allow such a crossing across the cellular junctions). Botox impedes synaptic junctions between nerve and muscle cells in the body as its mechanism of action; but would effect the same junctions in nerve to nerve junctions (neuronal synapses); so that would explain the "perception issues" I have noticed. That's my theory anyway. Some of my theories turn out to be right, this one has a high probability I believe.
OK, hyjack over, back to NADH. I will also be ordering a lot of D-Ribose at the same time. They both assist mitochodrial function: more energy, less pain.
Biologist